Investigational Oral Treatment for Adults with Type 2 Diabetes and Excess Weight
We are looking for adults aged 18–79 years who are overweight and living with type 2 diabetes to take part in a clinical research study evaluating an investigational oral medication.
Study overview
This study is evaluating an investigational oral medication for adults who are overweight and living with type 2 diabetes. Researchers are exploring whether this investigational medication may help improve blood sugar management and weight-related health outcomes when compared with a placebo. Participants will be randomly assigned to receive either the investigational medication or placebo. There is a 40% chance of receiving the placebo. The study will also assess how safe and well tolerated the medication is over time.
Am I eligible?
You may be eligible if:
- You are aged 18–79 years
- You have a BMI of 27 kg/m² or higher
- You are living with type 2 diabetes
- Your HbA1c is between 6.5% and 10%
- You have been on stable type 2 diabetes treatment for at least 90 days
- You are currently managing diabetes with diet/exercise or up to 3 oral diabetes medications
- You are not currently using GLP-1 receptor agonists or DPP-4 inhibitor medications
- You are willing to attend scheduled study visits and assessments
- You are able to commit to the full study duration of up to approximately 85 weeks
Indicative only. Eligibility is confirmed by our team at screening.
What taking part involves
If eligible, you will take part in the study for up to approximately 85 weeks. Participants will take a once-daily investigational oral medication or placebo and attend approximately 18 clinic visits and 5 phone calls throughout the study.
Researchers will closely monitor participants through regular health checks and study assessments. Procedures may include fasting visits, blood tests, ECGs, physical examinations, weight and waist measurements, questionnaires, and other routine safety assessments.
Because some study visits require fasting blood tests, participants will need to be available to attend morning clinic appointments for certain visits throughout the study. Refreshments will be provided on site.
- 1
Enquiry & phone call
We call to explain the study and answer your questions.
- 2
Screening visit
Meet the team and have health checks to confirm eligibility.
- 3
Study visits
Regular visits with expert care and health monitoring.
- 4
Final visit & follow-up
A wrap-up check and a thank-you for helping research.
Still have questions?
Our team is happy to talk it through. Call 1300 742 326.
Frequently asked questions
A clinical trial is a research study involving volunteers that helps researchers evaluate new treatments, medications, medical devices or approaches to healthcare. Clinical trials help determine whether these interventions are safe, effective and appropriate for wider use.
Clinical trials help advance healthcare by showing how treatments work, identifying possible side effects and exploring new ways to prevent, diagnose and manage medical conditions. By taking part, volunteers contribute to knowledge that may benefit people in the future.
Each trial has its own eligibility criteria, which may relate to your age, medical history, health conditions or current medications. Some studies are for people with a specific condition, while others involve healthy volunteers. Our research team can help you understand whether a study may be suitable.
Participant safety and wellbeing are central to clinical research. In Australia, trials must meet strict ethical and regulatory requirements and are reviewed by a Human Research Ethics Committee (HREC). Participants are monitored throughout the study.
All clinical trials involve some uncertainty and level of risk. Before you decide, the research team will explain the known and potential risks, possible benefits and available alternatives.