Investigational Treatment for Type 2 Diabetes and Obesity
The purpose of this study is to evaluate how safe and effective the investigational medicine is when taken over a longer period in adults with type 2 diabetes who are overweight or living with obesity.
Study overview
The purpose of this study is to evaluate how safe and effective the investigational medicine is when taken over a longer period in adults with type 2 diabetes who are overweight or living with obesity.
Am I eligible?
You may be eligible if:
- You are 18 years or older
- You have been diagnosed with type 2 diabetes
- You have a BMI of 27 kg/m² or higher
- You are not currently taking a GLP-1
- Your diabetes is managed with diet/exercise alone or stable oral medication
- You have tried to lose weight with diet and exercise without long-term success
- You are willing to attend regular morning, fasted clinic visits
- You are willing to self-administer a once-weekly injection
- You are willing to perform finger-stick blood glucose monitoring
- You are using reliable contraception (if applicable)
Indicative only. Eligibility is confirmed by our team at screening.
What taking part involves
If eligible, you will take part in the study for up to 79 weeks, including screening, treatment, and a safety follow-up period. The study involves 17 clinic visits and 6 phone calls, with clinic visits occurring approximately once every 4 weeks. Most clinic visits require fasting and will take place during clinic business hours Monday to Friday, 8am–4pm.
During the study, you will receive a once-weekly subcutaneous (under the skin) self-injection of either the investigational medicine or a placebo. Participants are randomly assigned to treatment groups, and neither you nor the study team will know which treatment you are receiving.
Throughout the study, doctors and nurses will closely monitor your blood glucose levels, body weight, and overall health through regular check-ups and testing.
Study assessments may include physical examinations, vital signs, ECGs, blood tests, urine screening, weight and BMI measurements, functional assessments, pregnancy testing (if applicable), lifestyle support reviews, diabetes education, and professional nutrition counselling.
Before enrolling, the study doctor and clinical team will explain the study in detail, including findings from previous research, potential risks and benefits, and what participation involves.
- 1
Enquiry & phone call
We call to explain the study and answer your questions.
- 2
Screening visit
Meet the team and have health checks to confirm eligibility.
- 3
Study visits
Regular visits with expert care and health monitoring.
- 4
Final visit & follow-up
A wrap-up check and a thank-you for helping research.
Still have questions?
Our team is happy to talk it through. Call 1300 742 326.
Frequently asked questions
A clinical trial is a research study involving volunteers that helps researchers evaluate new treatments, medications, medical devices or approaches to healthcare. Clinical trials help determine whether these interventions are safe, effective and appropriate for wider use.
Clinical trials help advance healthcare by showing how treatments work, identifying possible side effects and exploring new ways to prevent, diagnose and manage medical conditions. By taking part, volunteers contribute to knowledge that may benefit people in the future.
Each trial has its own eligibility criteria, which may relate to your age, medical history, health conditions or current medications. Some studies are for people with a specific condition, while others involve healthy volunteers. Our research team can help you understand whether a study may be suitable.
Participant safety and wellbeing are central to clinical research. In Australia, trials must meet strict ethical and regulatory requirements and are reviewed by a Human Research Ethics Committee (HREC). Participants are monitored throughout the study.
All clinical trials involve some uncertainty and level of risk. Before you decide, the research team will explain the known and potential risks, possible benefits and available alternatives.