Kidney Disease and High Uric Acid Study
This study is evaluating an investigational treatment for adults living with chronic kidney disease (CKD) who also have high uric acid levels.
Study overview
This study is evaluating an investigational treatment for adults living with chronic kidney disease (CKD) who also have high uric acid levels.
High uric acid is common in people with CKD and may increase the risk of gout and place additional strain on the kidneys over time. Researchers want to learn whether this investigational treatment may help lower uric acid levels and support kidney health alongside standard care.
The study will assess how safe the treatment is and how well it works over a longer period of time.
Am I eligible?
You may be eligible if:
- You are 18 to 75 years old
- You have been diagnosed with CKD for at least 3 months prior to enrolling on the study
- You have high uric acid levels
- You have a BMI between 18 and 40
- You are willing to attend clinic visits and complete study health checks
- You are using reliable contraception, if applicable
What taking part involves
If eligible, you will take part in the study for up to 46 weeks, including screening, treatment, and a safety follow-up period. The study involves 11 clinic visits. All visits will require fasting blood tests, so participants must be available for early morning appointments. Clinic visits will take place during clinic business hours on weekdays, between 9am–5pm.
During the study, you will receive one of the study treatment options: either a combination of the investigational medicine and a registered comparator (Febuxostat), investigational medicine alone, or placebo. Participants are randomly assigned to a treatment group, and neither you nor the study team will know which treatment option you are receiving.
Throughout the study, doctors and nurses will closely monitor your uric acid levels, kidney function, and overall health through regular check-ups and testing.
Study assessments may include medical history collection, physical examinations, vital signs, blood tests, urine tests, abdominal and kidney ultrasound, pregnancy testing if applicable, and monitoring for side effects.
Before enrolling, the study doctor and clinical team will explain the study in detail, including information from previous research, potential risks and benefits, and what participation involves.
- 1
Enquiry & phone call
We call to explain the study and answer your questions.
- 2
Screening visit
Meet the team and have health checks to confirm eligibility.
- 3
Study visits
Regular visits with expert care and health monitoring.
- 4
Final visit & follow-up
A wrap-up check and a thank-you for helping research.
Still have questions?
Our team is happy to talk it through. Call 1300 742 326.
Frequently asked questions
A clinical trial is a research study involving volunteers that helps researchers evaluate new treatments, medications, medical devices or approaches to healthcare. Clinical trials help determine whether these interventions are safe, effective and appropriate for wider use.
Clinical trials help advance healthcare by showing how treatments work, identifying possible side effects and exploring new ways to prevent, diagnose and manage medical conditions. By taking part, volunteers contribute to knowledge that may benefit people in the future.
Each trial has its own eligibility criteria, which may relate to your age, medical history, health conditions or current medications. Some studies are for people with a specific condition, while others involve healthy volunteers. Our research team can help you understand whether a study may be suitable.
Participant safety and wellbeing are central to clinical research. In Australia, trials must meet strict ethical and regulatory requirements and are reviewed by a Human Research Ethics Committee (HREC). Participants are monitored throughout the study.
All clinical trials involve some uncertainty and level of risk. Before you decide, the research team will explain the known and potential risks, possible benefits and available alternatives.