Injectable Treatment for Preventing Depression Relapse
This clinical research study is exploring an investigational treatment used alongside usual care for adults living with depression.
Study overview
This clinical research study is exploring an investigational treatment used alongside usual care for adults living with depression.
Depression is a condition that can change over time. While many people respond well to treatment, it’s common for symptoms to return after a period of feeling better.
Researchers are looking at whether a once‑weekly injectable treatment, when added to existing prescribed treatment, may help delay the return of symptoms and support people in maintaining their wellbeing over time.
Am I eligible?
You may be eligible if you:
- Are aged 18 to 75 years
- Have been diagnosed with depression
- Are currently feeling well or have only mild symptoms
- Are receiving stable prescribed treatment
- Are willing to continue your current treatment during the study
- Are able to attend study visits and complete assessments
- Are willing to self‑administer a weekly injection
What taking part involves
If you are eligible, participation in this study will begin with a screening period of approximately 4 weeks to confirm whether the study is suitable for you.
Following screening, participants will enter the treatment phase and remain in the study until certain study criteria are met. The overall length of participation may vary between individuals.
Participants will be randomly assigned to receive either the investigational treatment or a placebo (inactive treatment). Neither you nor the study team will know which treatment you are receiving during the study. The study treatment is self‑administered as a once‑weekly injection under the skin. You will attend regular clinic visits, approximately every 4 weeks, where the study team will carry out assessments and provide ongoing support. These visits may include questionnaires, health checks, and other routine assessments. Throughout the study, researchers will monitor your mood, day‑to‑day functioning, overall health, and safety. Clinic visits will take place during business hours of 9am–5pm, Monday–Friday.
- 1
Enquiry & phone call
We call to explain the study and answer your questions.
- 2
Screening visit
Meet the team and have health checks to confirm eligibility.
- 3
Study visits
Regular visits with expert care and health monitoring.
- 4
Final visit & follow-up
A wrap-up check and a thank-you for helping research.
Still have questions?
Our team is happy to talk it through. Call 1300 742 326.
Frequently asked questions
A clinical trial is a research study involving volunteers that helps researchers evaluate new treatments, medications, medical devices or approaches to healthcare. Clinical trials help determine whether these interventions are safe, effective and appropriate for wider use.
Clinical trials help advance healthcare by showing how treatments work, identifying possible side effects and exploring new ways to prevent, diagnose and manage medical conditions. By taking part, volunteers contribute to knowledge that may benefit people in the future.
Each trial has its own eligibility criteria, which may relate to your age, medical history, health conditions or current medications. Some studies are for people with a specific condition, while others involve healthy volunteers. Our research team can help you understand whether a study may be suitable.
Participant safety and wellbeing are central to clinical research. In Australia, trials must meet strict ethical and regulatory requirements and are reviewed by a Human Research Ethics Committee (HREC). Participants are monitored throughout the study.
All clinical trials involve some uncertainty and level of risk. Before you decide, the research team will explain the known and potential risks, possible benefits and available alternatives.