Atopic Dermatitis Study
Atopic dermatitis (eczema) is a long-term inflammatory skin condition that causes itching, redness, and flare-ups that can make daily life difficult. It often begins in childhood but can occur at any age.
Study overview
Atopic dermatitis (eczema) is a long-term inflammatory skin condition that causes itching, redness, and flare-ups that can make daily life difficult. It often begins in childhood but can occur at any age.
Many people continue to experience uncontrolled symptoms even with available medicines, as well as side effects.
This study is evaluating a new investigational medicine that may help treat atopic dermatitis symptoms in adults with moderate to severe atopic dermatitis.
The investigational medicine is designed to target a specific immune pathway that helps the body’s own cells control inflammation. By supporting this natural immune balance, the medicine may help reduce flare-ups, calm inflammation, and support skin healing without broadly suppressing the immune system.
Am I eligible?
You may be eligible if:
- You are an adult aged 18–70 years with moderate to severe atopic dermatitis (eczema)
- You have had a confirmed diagnosis of atopic dermatitis for at least 12 months prior to screening
- You are willing to attend regular study visits and assessments over the study period
- You are using reliable contraception, if applicable
- You agree to abstain from the use of THC-containing products while on study
- You are able to commit to the study schedule, which may involve participation for up to approximately 9 months
What taking part involves
If eligible, you will take part in the study for approximately 9 months, including screening, treatment, optional crossover treatment and follow-up.
The study involves 16 clinic visits, including 8 fasting visits, and regular health and skin assessments throughout the treatment and follow-up periods.
Participants will attend regular clinic visits throughout screening, treatment, optional crossover treatment and follow-up periods, including several fasting visits and ongoing skin and health assessments.
Participants will receive subcutaneous, under the skin, injections of either the investigational medicine or placebo once every four weeks during the initial 12-week treatment period. Participants who consent will receive additional treatment as part of the study.
During the study, participants will undergo comprehensive health and skin assessments, including:
- Medical history collection
- Physical examinations
- Vital signs and ECGs
- Blood tests, 16 total
- Skin imaging and lesion photography
- Skin biopsy, to be conducted at Paratus Clinical Research Brisbane only, and tape strip sampling
- Itch, symptom and quality of life questionnaires
- Pregnancy testing, if applicable
These assessments will help the study team monitor safety, treatment response, and changes in skin health over time.
- 1
Enquiry & phone call
We call to explain the study and answer your questions.
- 2
Screening visit
Meet the team and have health checks to confirm eligibility.
- 3
Study visits
Regular visits with expert care and health monitoring.
- 4
Final visit & follow-up
A wrap-up check and a thank-you for helping research.
Still have questions?
Our team is happy to talk it through. Call 1300 742 326.
Frequently asked questions
A clinical trial is a research study involving volunteers that helps researchers evaluate new treatments, medications, medical devices or approaches to healthcare. Clinical trials help determine whether these interventions are safe, effective and appropriate for wider use.
Clinical trials help advance healthcare by showing how treatments work, identifying possible side effects and exploring new ways to prevent, diagnose and manage medical conditions. By taking part, volunteers contribute to knowledge that may benefit people in the future.
Each trial has its own eligibility criteria, which may relate to your age, medical history, health conditions or current medications. Some studies are for people with a specific condition, while others involve healthy volunteers. Our research team can help you understand whether a study may be suitable.
Participant safety and wellbeing are central to clinical research. In Australia, trials must meet strict ethical and regulatory requirements and are reviewed by a Human Research Ethics Committee (HREC). Participants are monitored throughout the study.
All clinical trials involve some uncertainty and level of risk. Before you decide, the research team will explain the known and potential risks, possible benefits and available alternatives.