Research Study for Adults with Obesity and Associated Health Conditions
Obesity is a complex chronic condition that can increase the risk of other health problems, including high blood pressure, high cholesterol, sleep apnoea, heart disease, and type 2 diabetes. Researchers are studying whether two investigational medicines, used together as self-administered injections, can help with weight management.
Study overview
Obesity is a complex chronic condition that can increase the risk of other health problems, including high blood pressure, high cholesterol, sleep apnoea, heart disease, and type 2 diabetes. Researchers are studying whether two investigational medicines, used together as self-administered injections, can help with weight management.
If you’ve been trying to lose weight and are interested in exploring alternative treatment options, this may be an opportunity to take part in research aimed at improving future weight management treatments.
Am I eligible?
You may be eligible if:
- You are 18 years of age or older
- You have BMI 30 or higher, or BMI 27–30 with a weight-related health condition (e.g., high blood pressure, high cholesterol, sleep apnoea, or heart disease)
- You have previously tried to lose weight through diet without long-term success
- You have not used GLP-1 receptor agonists or any weight-loss medications within the past 6 months
- You are willing to attend scheduled study visits and assessments
- You are able to commit to the full study duration (approximately 52 weeks)
- Able and willing to self-administer subcutaneous injections
Indicative only. Eligibility is confirmed by our team at screening.
What taking part involves
The study runs for approximately 52 weeks and includes 13 clinic visits. Participants will receive weekly self-administered injections of either the investigational medicine or placebo. The investigational medicines will be given subcutaneously or under the skin.
Doctors and nurses will closely monitor participants throughout the study with regular health assessments and weight measurements.
- 1
Enquiry & phone call
We call to explain the study and answer your questions.
- 2
Screening visit
Meet the team and have health checks to confirm eligibility.
- 3
Study visits
Regular visits with expert care and health monitoring.
- 4
Final visit & follow-up
A wrap-up check and a thank-you for helping research.
Still have questions?
Our team is happy to talk it through. Call 1300 742 326.
Frequently asked questions
A clinical trial is a research study involving volunteers that helps researchers evaluate new treatments, medications, medical devices or approaches to healthcare. Clinical trials help determine whether these interventions are safe, effective and appropriate for wider use.
Clinical trials help advance healthcare by showing how treatments work, identifying possible side effects and exploring new ways to prevent, diagnose and manage medical conditions. By taking part, volunteers contribute to knowledge that may benefit people in the future.
Each trial has its own eligibility criteria, which may relate to your age, medical history, health conditions or current medications. Some studies are for people with a specific condition, while others involve healthy volunteers. Our research team can help you understand whether a study may be suitable.
Participant safety and wellbeing are central to clinical research. In Australia, trials must meet strict ethical and regulatory requirements and are reviewed by a Human Research Ethics Committee (HREC). Participants are monitored throughout the study.
All clinical trials involve some uncertainty and level of risk. Before you decide, the research team will explain the known and potential risks, possible benefits and available alternatives.